Puberty Induced Gingival Enlargement

The homeostasis of the periodontium involves complex multifactorial relationships, in which the endocrine system plays an important role [1]. Hormones are specific regulatory molecules that modulate function reproduction, growth and development and the maintenance of internal environments as well as energy production, utilization and storage [1]. As well as being the regulators of reproductive functions, sex steroid hormones have potent effects on the nervous and cardiovascular system, and on major determinants of the development and integrity of the skeleton and oral cavity including periodontal tissues [2]. Under the broad category of dental plaque induced gingival diseases that are modified by systemic factors, those associated with the endocrine system are classified as puberty, menstrual cycle and pregnancy associated gingivitis [3]. Researchers have shown that changes in periodontal conditions may be associated with variations in sex hormones [4].